Intrauterine programming of obesity and type 2 diabetes
نویسندگان
چکیده
منابع مشابه
Association of Intrauterine Exposure to Maternal Diabetes and Obesity With Type 2 Diabetes in Youth
OBJECTIVE Limited data exist on the association between in utero exposure to maternal diabetes and obesity and type 2 diabetes in diverse youth. These associations were explored in African-American, Hispanic, and non-Hispanic white youth participating in the SEARCH Case-Control Study. RESEARCH DESIGN AND METHODS A total of 79 youth with type 2 diabetes and 190 nondiabetic control youth aged 1...
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Obesity and type 2 diabetes (T2DM) are public health problems, with health consequences and economic costs that have raised concern worldwide. The increase in the prevalence of diabetes parallels that of obesity. Some experts call this dual epidemic “diabesity”. Elevated body mass index (BMI) and waist circumference (WC) were significantly associated T2DM. One consequence of obesity is an incre...
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Background: Perilipins are proteins at the external level of the lipid glob in adipocytes steroid-generating cells and play a central role in lipid storage and breakdown. FTO gene is associated with Type-2 diabetes (T2D) and increased fat mass. Association of Perilipin and FTO genes polymorphism with T2D was investigated. Methods: Clinical traits in a random sample of 183 Iranian men and wom...
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Abstract Objective: Adiponectin and vaspin are adipocyte-derived proteins and involved in the regulation of glucose metabolism and obesity related disorders. The mechanisms that adipokines might be linked to disturbance of glucose are unclear. Thus, this study investigated the levels of serum adiponectin and vaspin, blood lipid profiles, and abdominal obesity in type 2 diabetes (T2DM) patients...
متن کاملIntrauterine exposure to diabetes conveys risks for type 2 diabetes and obesity: a study of discordant sibships.
Intrauterine exposure to diabetes is associated with an excess of diabetes and obesity in the offspring, but the effects of intrauterine exposure are confounded by genetic factors. To determine the role of the intrauterine diabetic environment per se, the prevalence of diabetes and the mean BMI were compared in siblings born before and after their mother was recognized as having diabetes. Nucle...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 2019
ISSN: 0012-186X,1432-0428
DOI: 10.1007/s00125-019-4951-9